Sto. Niño Senior High School was opened coincidentally with the launching of the Senior High School of the K to 12 Program of the Department of Education on 2016. The establishment of the school was in fulfillment of the goal of the Department of Education to make Basic Education highly accessible to every Filipino child through the establishment of a school in every barangay across the country.

     On June 2016, Sto. Nino Senior High School was located at Parañaque National High School – Main. Because of the growing population of students and the finished building in the heart of Sto. Niño, the school transferred to its new location which is within Sto. Niño Elementary School on June 2017, which is today’s school address.

      As of today, Sto. Niño Senior High School is the only public stand-alone Senior High School in the Schools Division of Parañaque. Its official name is “Senior High School within Sto. Niño Elementary School”, which is now located at J.P. Rizal St., Brgy. Sto. Niño, Parañaque City.